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Pharmacological Characterization of Toludesvenlafaxine as a Triple Reuptake Inhibitor
Toludesvenlafaxine hydrochloride dihydrate is a novel chemical entity and a potential triple monoamine reuptake inhibitor. This study characterized the in vitro triple reuptake inhibition activity, antidepressant-like activity in animals, and pharmacokinetic profiles in rats of toludesvenlafaxine. B...
Autores principales: | Zhu, Haibo, Wang, Wenyan, Sha, Chunjie, Guo, Wei, Li, Chunmei, Zhao, Fengjuan, Wang, Hongbo, Jiang, Wanglin, Tian, Jingwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476831/ https://www.ncbi.nlm.nih.gov/pubmed/34594228 http://dx.doi.org/10.3389/fphar.2021.741794 |
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