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The Antimicrobial Peptide Human β-Defensin-3 Accelerates Wound Healing by Promoting Angiogenesis, Cell Migration, and Proliferation Through the FGFR/JAK2/STAT3 Signaling Pathway
In addition to its antimicrobial activity, the skin-derived antimicrobial peptide human β-defensin-3 (hBD-3) promotes keratinocyte proliferation and migration to initiate the wound healing process; however, its effects on fibroblasts, which are the major cell type responsible for wound healing, rema...
Autores principales: | Takahashi, Miho, Umehara, Yoshie, Yue, Hainan, Trujillo-Paez, Juan Valentin, Peng, Ge, Nguyen, Hai Le Thanh, Ikutama, Risa, Okumura, Ko, Ogawa, Hideoki, Ikeda, Shigaku, Niyonsaba, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476922/ https://www.ncbi.nlm.nih.gov/pubmed/34594328 http://dx.doi.org/10.3389/fimmu.2021.712781 |
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