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Rapid Characterization of Complex Killer Cell Immunoglobulin-Like Receptor (KIR) Regions Using Cas9 Enrichment and Nanopore Sequencing

Long-read sequencing approaches have considerably improved the quality and contiguity of genome assemblies. Such platforms bear the potential to resolve even extremely complex regions, such as multigenic immune families and repetitive stretches of DNA. Deep sequencing coverage, however, is required...

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Detalles Bibliográficos
Autores principales:	Bruijnesteijn, Jesse, van der Wiel, Marit, de Groot, Natasja G., Bontrop, Ronald E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476923/ https://www.ncbi.nlm.nih.gov/pubmed/34594334 http://dx.doi.org/10.3389/fimmu.2021.722181

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