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Anti-Carbamylated LL37 Antibodies Promote Pathogenic Bone Resorption in Rheumatoid Arthritis

OBJECTIVE: Antibodies against carbamylated proteins (anti-CarP) are associated with poor prognosis and the development of bone erosions in rheumatoid arthritis (RA). RA neutrophils externalize modified autoantigens through the formation of neutrophil extracellular traps (NETs). Increased levels of t...

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Detalles Bibliográficos
Autores principales: O’Neil, Liam J., Oliveira, Christopher B., Sandoval-Heglund, Donavon, Barrera-Vargas, Ana, Merayo-Chalico, Javier, Aguirre-Aguilar, Eduardo, Kaplan, Mariana J., Carmona-Rivera, Carmelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477029/
https://www.ncbi.nlm.nih.gov/pubmed/34594331
http://dx.doi.org/10.3389/fimmu.2021.715997