Cargando…

Anti-Carbamylated LL37 Antibodies Promote Pathogenic Bone Resorption in Rheumatoid Arthritis

OBJECTIVE: Antibodies against carbamylated proteins (anti-CarP) are associated with poor prognosis and the development of bone erosions in rheumatoid arthritis (RA). RA neutrophils externalize modified autoantigens through the formation of neutrophil extracellular traps (NETs). Increased levels of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	O’Neil, Liam J., Oliveira, Christopher B., Sandoval-Heglund, Donavon, Barrera-Vargas, Ana, Merayo-Chalico, Javier, Aguirre-Aguilar, Eduardo, Kaplan, Mariana J., Carmona-Rivera, Carmelo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477029/ https://www.ncbi.nlm.nih.gov/pubmed/34594331 http://dx.doi.org/10.3389/fimmu.2021.715997

Ejemplares similares

Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis
por: O’Neil, Liam J., et al.
Publicado: (2020)

Complementary Effects of Carbamylated and Citrullinated LL37 in Autoimmunity and Inflammation in Systemic Lupus Erythematosus
por: Lande, Roberto, et al.
Publicado: (2021)

Generation of Monoclonal Antibodies Specific for Native LL37 and Citrullinated LL37 That Discriminate the Two LL37 Forms in the Skin and Circulation of Cutaneous/Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients
por: Lande, Roberto, et al.
Publicado: (2020)

Citrullination and Carbamylation in the Pathophysiology of Rheumatoid Arthritis
por: Pruijn, Ger J. M.
Publicado: (2015)

LL-37 Triggers Antimicrobial Activity in Human Platelets
por: Sánchez-Peña, Francisco Javier, et al.
Publicado: (2023)

Anti-carbamylated protein antibodies in rheumatoid arthritis patients and their association with rheumatoid factor
por: Othman, Maizatul A., et al.
Publicado: (2017)

The Role of Cathelicidin LL-37 in Cancer Development
por: Piktel, Ewelina, et al.
Publicado: (2015)

Significance of LL-37 on Immunomodulation and Disease Outcome
por: Yang, Binbin, et al.
Publicado: (2020)

Regulation of LL-37 in Bone and Periodontium Regeneration
por: Chinipardaz, Zahra, et al.
Publicado: (2022)

Endogenous Carbamylation of Renal Medullary Proteins
por: Claxton, J'Neka S., et al.
Publicado: (2013)

Post-translational modifications in rheumatoid arthritis and atherosclerosis: Focus on citrullination and carbamylation
por: Spinelli, Francesca Romana, et al.
Publicado: (2016)

Carbamylation of vimentin is inducible by smoking and represents an independent autoantigen in rheumatoid arthritis
por: Ospelt, Caroline, et al.
Publicado: (2017)

Carbamylated albumin is one of the target antigens of anti-carbamylated protein antibodies
por: Nakabo, Shuichiro, et al.
Publicado: (2017)

Comparison of homocitrulline and carbamylated albumin as biomarkers of carbamylation reactions in hemodialyzed patients
por: Lenglet, Aurelie, et al.
Publicado: (2023)

Cathelicidin LL-37 in Health and Diseases of the Oral Cavity
por: Tokajuk, Joanna, et al.
Publicado: (2022)

Serum LL‐37 and inflammatory cytokines levels in psoriasis
por: Lao, Juanfeng, et al.
Publicado: (2023)

CXCR2 specific endocytosis of immunomodulatory peptide LL-37 in human monocytes and formation of LL-37 positive large vesicles in differentiated monoosteophils
por: Zhang, Zhifang, et al.
Publicado: (2019)

Carbamylated lipoproteins in diabetes
por: Denimal, Damien
Publicado: (2023)

The Role of Neutrophils and Neutrophil Extracellular Traps in Vascular Damage in Systemic Lupus Erythematosus
por: O’Neil, Liam J., et al.
Publicado: (2019)

Meta-Analysis: Diagnostic Accuracy of Anti-Carbamylated Protein Antibody for Rheumatoid Arthritis
por: Li, Liubing, et al.
Publicado: (2016)

Anti-carbamylated protein autoantibodies associated with mortality in Spanish rheumatoid arthritis patients
por: Vidal-Bralo, Laura, et al.
Publicado: (2017)

Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients
por: Spinelli, Francesca Romana, et al.
Publicado: (2017)

Impact of Posttranslational Modification in Pathogenesis of Rheumatoid Arthritis: Focusing on Citrullination, Carbamylation, and Acetylation
por: Kwon, Eui-Jong, et al.
Publicado: (2021)

Role of LL-37 in thrombotic complications in patients with COVID-19
por: Duan, Zilei, et al.
Publicado: (2022)

Impaired tolerance to the autoantigen LL-37 in acute coronary syndrome
por: Chernomordik, Fernando, et al.
Publicado: (2023)

Patient-reported outcomes in ANCA-associated vasculitis: a cross-sectional study to explore the interactions between patients’ and physicians’ perspectives
por: Hurtado-Arias, José Joel, et al.
Publicado: (2023)

Protein Carbamylation and Cardiovascular Disease
por: Verbrugge, Frederik H., et al.
Publicado: (2015)

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis
por: Shi, Jing, et al.
Publicado: (2015)

Anti-Carbamylated Protein Antibodies as a Reproducible Independent Type of Rheumatoid Arthritis Autoantibodies
por: Montes, Ariana, et al.
Publicado: (2016)

Erratum to: Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients
por: Spinelli, Francesca Romana, et al.
Publicado: (2017)

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis
por: Brink, Mikael, et al.
Publicado: (2016)

LL-37 at the local site of streptococcal skin and soft-tissue infections
por: Thulin, Pontus, et al.
Publicado: (2007)

Evaluation of the Ability of LL-37 to Neutralise LPS In Vitro and Ex Vivo
por: Scott, Aaron, et al.
Publicado: (2011)

Vesicular LL-37 Contributes to Inflammation of the Lesional Skin of Palmoplantar Pustulosis
por: Murakami, Masamoto, et al.
Publicado: (2014)

Serum Levels of LL-37 and Inflammatory Cytokines in Plaque and Guttate Psoriasis
por: Hwang, Young Ji, et al.
Publicado: (2014)

LL-37 Induces Polymerization and Bundling of Actin and Affects Actin Structure
por: Sol, Asaf, et al.
Publicado: (2012)

Antimicrobial peptide LL-37 participates in the transcriptional regulation of melanoma cells
por: Muñoz, Mindy, et al.
Publicado: (2016)

Antimicrobial peptide LL-37 is bactericidal against Staphylococcus aureus biofilms
por: Kang, Jason, et al.
Publicado: (2019)

Pulmonary defense and the human cathelicidin hCAP-18/LL-37
por: Fahy, R. J., et al.
Publicado: (2005)

Synergistic Anti-Staphylococcal Activity Of Niosomal Recombinant Lysostaphin-LL-37
por: Sadeghi, Somayeh, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_69a6kp7lg7jd5035ad33ifqm0g