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Neurological complications of COVID-19: from pathophysiology to rehabilitation. An overview

OBJECTIVE: To evaluate how the SARS-COV2 is able to affect the nervous system, the main neurological manifestation, and the treatment used, including neurorehabilitation. METHODS: Studies performed during the current year that fulfilled inclusion criteria were selected from PubMed, Scopus, Cochrane,...

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Detalles Bibliográficos
Autores principales: Raciti, Loredana, Calabrò, Rocco Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477084/
https://www.ncbi.nlm.nih.gov/pubmed/34487099
http://dx.doi.org/10.23750/abm.v92i4.10620
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author Raciti, Loredana
Calabrò, Rocco Salvatore
author_facet Raciti, Loredana
Calabrò, Rocco Salvatore
author_sort Raciti, Loredana
collection PubMed
description OBJECTIVE: To evaluate how the SARS-COV2 is able to affect the nervous system, the main neurological manifestation, and the treatment used, including neurorehabilitation. METHODS: Studies performed during the current year that fulfilled inclusion criteria were selected from PubMed, Scopus, Cochrane, and Web of Sciences databases. The search combined the terms “Covid 19,” “rehabilitation/treatment,” and “neurological complications.” RESULTS: The exact route by which SARS-CoV-2 can penetrate the CNS is still unknown, although a possible retrograde transynaptic pathway from peripheral nerve endings, and/or through the olfactory bulb, have been suggested. An early management of COVID-19 by a multiprofessional team is fundamental to avoid long term sequaele. Rehabilitation is recommended to improve respiratory and cardiac function, as well as to avoid long term neurological complications. CONCLUSIONS: As no specific conclusions in term of prognosis and treatment could be done, research and consensus paper are needed to provide NeuroCovid patients with the best treatment options, including neurorehabilitation. (www.actabiomedica.it)
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spelling pubmed-84770842021-10-08 Neurological complications of COVID-19: from pathophysiology to rehabilitation. An overview Raciti, Loredana Calabrò, Rocco Salvatore Acta Biomed Reviews/Focus on OBJECTIVE: To evaluate how the SARS-COV2 is able to affect the nervous system, the main neurological manifestation, and the treatment used, including neurorehabilitation. METHODS: Studies performed during the current year that fulfilled inclusion criteria were selected from PubMed, Scopus, Cochrane, and Web of Sciences databases. The search combined the terms “Covid 19,” “rehabilitation/treatment,” and “neurological complications.” RESULTS: The exact route by which SARS-CoV-2 can penetrate the CNS is still unknown, although a possible retrograde transynaptic pathway from peripheral nerve endings, and/or through the olfactory bulb, have been suggested. An early management of COVID-19 by a multiprofessional team is fundamental to avoid long term sequaele. Rehabilitation is recommended to improve respiratory and cardiac function, as well as to avoid long term neurological complications. CONCLUSIONS: As no specific conclusions in term of prognosis and treatment could be done, research and consensus paper are needed to provide NeuroCovid patients with the best treatment options, including neurorehabilitation. (www.actabiomedica.it) Mattioli 1885 2021 2021-09-02 /pmc/articles/PMC8477084/ /pubmed/34487099 http://dx.doi.org/10.23750/abm.v92i4.10620 Text en Copyright: © 2021 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Reviews/Focus on
Raciti, Loredana
Calabrò, Rocco Salvatore
Neurological complications of COVID-19: from pathophysiology to rehabilitation. An overview
title Neurological complications of COVID-19: from pathophysiology to rehabilitation. An overview
title_full Neurological complications of COVID-19: from pathophysiology to rehabilitation. An overview
title_fullStr Neurological complications of COVID-19: from pathophysiology to rehabilitation. An overview
title_full_unstemmed Neurological complications of COVID-19: from pathophysiology to rehabilitation. An overview
title_short Neurological complications of COVID-19: from pathophysiology to rehabilitation. An overview
title_sort neurological complications of covid-19: from pathophysiology to rehabilitation. an overview
topic Reviews/Focus on
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477084/
https://www.ncbi.nlm.nih.gov/pubmed/34487099
http://dx.doi.org/10.23750/abm.v92i4.10620
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