A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide

Cyclotriazadisulfonamide (CADA) inhibits the cotranslational translocation of type I integral membrane protein human CD4 (huCD4) across the endoplasmic reticulum in a signal peptide (SP)–dependent way. Previously, sortilin was identified as a secondary substrate for CADA but showed reduced CADA sens...

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Detalles Bibliográficos
Autores principales: Pauwels, Eva, Rutz, Claudia, Provinciael, Becky, Stroobants, Joren, Schols, Dominique, Hartmann, Enno, Krause, Eberhard, Stephanowitz, Heike, Schülein, Ralf, Vermeire, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477212/
https://www.ncbi.nlm.nih.gov/pubmed/34481949
http://dx.doi.org/10.1016/j.mcpro.2021.100144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477212/
https://www.ncbi.nlm.nih.gov/pubmed/34481949
http://dx.doi.org/10.1016/j.mcpro.2021.100144

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