A Rare Case Report of Malignant Peripheral Nerve Sheath Tumor Involving Both the Small Bowel and Large Bowel

Malignant peripheral nerve sheath tumor (MPNST) contains properties and histologic markers of both neural crest cells and mesenchymal cells. It is a rare diagnosis, with an incidence of 1:100,000/year or 4%–10% of soft-tissue sarcomas. There are very few cases reported and studied. Therefore, establ...

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Autores principales: Khan, Nazia, Hashmi, Irma, Atallah, Liana, Shaaban, Hamid, Guron, Gunwant, Fedida, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477282/
https://www.ncbi.nlm.nih.gov/pubmed/34558453
http://dx.doi.org/10.4103/aam.aam_10_20
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author Khan, Nazia
Hashmi, Irma
Atallah, Liana
Shaaban, Hamid
Guron, Gunwant
Fedida, Andre
author_facet Khan, Nazia
Hashmi, Irma
Atallah, Liana
Shaaban, Hamid
Guron, Gunwant
Fedida, Andre
author_sort Khan, Nazia
collection PubMed
description Malignant peripheral nerve sheath tumor (MPNST) contains properties and histologic markers of both neural crest cells and mesenchymal cells. It is a rare diagnosis, with an incidence of 1:100,000/year or 4%–10% of soft-tissue sarcomas. There are very few cases reported and studied. Therefore, establishing a proper diagnosis and treatment of MPNST provides a challenge. We present this unique and rare case of metastatic MPNST of the small and large bowel with bone, pulmonary, liver, and splenic metastases. The patient subsequently developed hemorrhagic brain metastases and died 6 months after THE initial diagnosis.
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spelling pubmed-84772822021-10-14 A Rare Case Report of Malignant Peripheral Nerve Sheath Tumor Involving Both the Small Bowel and Large Bowel Khan, Nazia Hashmi, Irma Atallah, Liana Shaaban, Hamid Guron, Gunwant Fedida, Andre Ann Afr Med Case Report Malignant peripheral nerve sheath tumor (MPNST) contains properties and histologic markers of both neural crest cells and mesenchymal cells. It is a rare diagnosis, with an incidence of 1:100,000/year or 4%–10% of soft-tissue sarcomas. There are very few cases reported and studied. Therefore, establishing a proper diagnosis and treatment of MPNST provides a challenge. We present this unique and rare case of metastatic MPNST of the small and large bowel with bone, pulmonary, liver, and splenic metastases. The patient subsequently developed hemorrhagic brain metastases and died 6 months after THE initial diagnosis. Medknow Publications & Media Pvt Ltd 2021 2021-09-17 /pmc/articles/PMC8477282/ /pubmed/34558453 http://dx.doi.org/10.4103/aam.aam_10_20 Text en Copyright: © 2021 Annals of African Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Khan, Nazia
Hashmi, Irma
Atallah, Liana
Shaaban, Hamid
Guron, Gunwant
Fedida, Andre
A Rare Case Report of Malignant Peripheral Nerve Sheath Tumor Involving Both the Small Bowel and Large Bowel
title A Rare Case Report of Malignant Peripheral Nerve Sheath Tumor Involving Both the Small Bowel and Large Bowel
title_full A Rare Case Report of Malignant Peripheral Nerve Sheath Tumor Involving Both the Small Bowel and Large Bowel
title_fullStr A Rare Case Report of Malignant Peripheral Nerve Sheath Tumor Involving Both the Small Bowel and Large Bowel
title_full_unstemmed A Rare Case Report of Malignant Peripheral Nerve Sheath Tumor Involving Both the Small Bowel and Large Bowel
title_short A Rare Case Report of Malignant Peripheral Nerve Sheath Tumor Involving Both the Small Bowel and Large Bowel
title_sort rare case report of malignant peripheral nerve sheath tumor involving both the small bowel and large bowel
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477282/
https://www.ncbi.nlm.nih.gov/pubmed/34558453
http://dx.doi.org/10.4103/aam.aam_10_20
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