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Prevalence of Obstructive Sleep Apnea in Diabetic Patients
CONTEXT: Obstructive sleep apnea (OSA)-related hypoxemia stimulates release of acute-phase proteins and reactive oxygen species that exacerbate insulin resistance and lipolysis and cause an augmented prothrombotic and proinflammatory state which can leads to premature death. AIMS: This study aims to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477286/ https://www.ncbi.nlm.nih.gov/pubmed/34558450 http://dx.doi.org/10.4103/aam.aam_43_20 |
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author | Singh, Ankita Chaudhary, Shyam Chand Gupta, Kamlesh K. Sawlani, Kamal K. Singh, Abhishek Singh, Abhishek B. Verma, Ajay K. |
author_facet | Singh, Ankita Chaudhary, Shyam Chand Gupta, Kamlesh K. Sawlani, Kamal K. Singh, Abhishek Singh, Abhishek B. Verma, Ajay K. |
author_sort | Singh, Ankita |
collection | PubMed |
description | CONTEXT: Obstructive sleep apnea (OSA)-related hypoxemia stimulates release of acute-phase proteins and reactive oxygen species that exacerbate insulin resistance and lipolysis and cause an augmented prothrombotic and proinflammatory state which can leads to premature death. AIMS: This study aims to study the prevalence of OSA in diabetic patients. SETTING AND DESIGN: It was a cross-sectional study, done over a period of 1 year in a tertiary care hospital. MATERIALS AND METHODS: A total of 149 type 2 diabetic patients were enrolled after taking written consent. All patients were subjected to STOP BANG questionnaire and patients falling in intermediate-high risk (score 3–8), were taken for overnight polysomnography to confirm the diagnosis of OSA (apnea hypopnea index ≥ 5). STATISTICAL ANALYSIS USED: Statistical Package for Social Sciences (SPSS) Version 21.0 statistical analysis software. RESULTS: Fifty-five percent of our diabetic population were having OSA. The age of patients enrolled in the study ranged between 30 and 86 years and prevalence increases with an increase in age groups. Majority (61.7%) of our cases were males. Incremental trend in weight, body mass index (BMI), neck circumference, and waist circumference of OSA cases were found with increasing in severity of OSA. Mean levels of raised blood sugar and HbA1c were higher in severe OSA cases. CONCLUSIONS: OSA has a high prevalence in patients with type 2 diabetes mellitus. Patients with type 2 diabetes should be screened for OSA, even in the absence of symptoms, especially in individuals with higher waist circumference and BMI. |
format | Online Article Text |
id | pubmed-8477286 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-84772862021-10-14 Prevalence of Obstructive Sleep Apnea in Diabetic Patients Singh, Ankita Chaudhary, Shyam Chand Gupta, Kamlesh K. Sawlani, Kamal K. Singh, Abhishek Singh, Abhishek B. Verma, Ajay K. Ann Afr Med Original Article CONTEXT: Obstructive sleep apnea (OSA)-related hypoxemia stimulates release of acute-phase proteins and reactive oxygen species that exacerbate insulin resistance and lipolysis and cause an augmented prothrombotic and proinflammatory state which can leads to premature death. AIMS: This study aims to study the prevalence of OSA in diabetic patients. SETTING AND DESIGN: It was a cross-sectional study, done over a period of 1 year in a tertiary care hospital. MATERIALS AND METHODS: A total of 149 type 2 diabetic patients were enrolled after taking written consent. All patients were subjected to STOP BANG questionnaire and patients falling in intermediate-high risk (score 3–8), were taken for overnight polysomnography to confirm the diagnosis of OSA (apnea hypopnea index ≥ 5). STATISTICAL ANALYSIS USED: Statistical Package for Social Sciences (SPSS) Version 21.0 statistical analysis software. RESULTS: Fifty-five percent of our diabetic population were having OSA. The age of patients enrolled in the study ranged between 30 and 86 years and prevalence increases with an increase in age groups. Majority (61.7%) of our cases were males. Incremental trend in weight, body mass index (BMI), neck circumference, and waist circumference of OSA cases were found with increasing in severity of OSA. Mean levels of raised blood sugar and HbA1c were higher in severe OSA cases. CONCLUSIONS: OSA has a high prevalence in patients with type 2 diabetes mellitus. Patients with type 2 diabetes should be screened for OSA, even in the absence of symptoms, especially in individuals with higher waist circumference and BMI. Medknow Publications & Media Pvt Ltd 2021 2021-09-17 /pmc/articles/PMC8477286/ /pubmed/34558450 http://dx.doi.org/10.4103/aam.aam_43_20 Text en Copyright: © 2021 Annals of African Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Singh, Ankita Chaudhary, Shyam Chand Gupta, Kamlesh K. Sawlani, Kamal K. Singh, Abhishek Singh, Abhishek B. Verma, Ajay K. Prevalence of Obstructive Sleep Apnea in Diabetic Patients |
title | Prevalence of Obstructive Sleep Apnea in Diabetic Patients |
title_full | Prevalence of Obstructive Sleep Apnea in Diabetic Patients |
title_fullStr | Prevalence of Obstructive Sleep Apnea in Diabetic Patients |
title_full_unstemmed | Prevalence of Obstructive Sleep Apnea in Diabetic Patients |
title_short | Prevalence of Obstructive Sleep Apnea in Diabetic Patients |
title_sort | prevalence of obstructive sleep apnea in diabetic patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477286/ https://www.ncbi.nlm.nih.gov/pubmed/34558450 http://dx.doi.org/10.4103/aam.aam_43_20 |
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