Molecular Modeling and Bioinformatics Analysis of Drug-Receptor Interactions in the System Formed by Glargine, Its Metabolite M1, the Insulin Receptor, and the IGF1 Receptor

INTRODUCTION: Insulin and insulin-like growth factor type 1 (IGF1) regulate multiple physiological functions by acting on the insulin receptor (IR) and insulin-like growth factor type 1 receptor (IGF1R). The insulin analog glargine differs from insulin in three residues (Gly(A21), Arg(B31), Arg(B32)...

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Detalles Bibliográficos
Autores principales: González-Beltrán, Margarita, Gómez-Alegría, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477355/
https://www.ncbi.nlm.nih.gov/pubmed/34594103
http://dx.doi.org/10.1177/11779322211046403

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