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2D Strategy for the Construction of an Enzyme-Activated NIR Fluorophore Suitable for the Visual Sensing and Profiling of Homologous Nitroreductases from Various Bacterial Species

[Image: see text] Nitroreductases (NTRs) mediate the reduction of nitroaromatic compounds to the corresponding nitrite, hydroxylamine, or amino derivatives. The activity of NTRs in bacteria facilitates the metabolic activation and antibacterial activity of 5-nitroimidazoles. Therefore, NTR activity...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Wang, Yifei, Feng, Lei, Tian, Xiangge, Cui, Jingnan, Yu, Zhenlong, Wang, Chao, Zhang, Baojing, James, Tony D., Ma, Xiaochi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477384/
https://www.ncbi.nlm.nih.gov/pubmed/34469146
http://dx.doi.org/10.1021/acssensors.1c01216