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NMR studies of group 8 metallodrugs: (187)Os-enriched organo-osmium half-sandwich anticancer complex

We report the synthesis of the organo-osmium anticancer complex [Os(η(6)-p-cym)(N,N-azpy-NMe(2))Br]PF(6) (1) containing natural abundance (187)Os (1.96%), and isotopically-enriched (98%) [(187)Os]-1. Complex 1 and [(187)Os]-1 contain a π-bonded para-cymene (p-cym), a chelated 4-(2-pyridylazo)-N,N-di...

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Detalles Bibliográficos
Autores principales:	Needham, Russell J., Prokes, Ivan, Habtemariam, Abraha, Romero-Canelón, Isolda, Clarkson, Guy J., Sadler, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477448/ https://www.ncbi.nlm.nih.gov/pubmed/34581369 http://dx.doi.org/10.1039/d1dt02213j

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