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Age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females
BACKGROUND: In aging, muscle stiffness is considered as one of the factors associated with the reduction of force generation capability. There have been inconsistent findings on age-related alteration in the passive stiffness of quadriceps muscle in the female adults. Thus, the aim of this study was...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477537/ https://www.ncbi.nlm.nih.gov/pubmed/34579696 http://dx.doi.org/10.1186/s12891-021-04519-8 |
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author | Xu, Jingfei Fu, Siu Ngor Hug, François |
author_facet | Xu, Jingfei Fu, Siu Ngor Hug, François |
author_sort | Xu, Jingfei |
collection | PubMed |
description | BACKGROUND: In aging, muscle stiffness is considered as one of the factors associated with the reduction of force generation capability. There have been inconsistent findings on age-related alteration in the passive stiffness of quadriceps muscle in the female adults. Thus, the aim of this study was to determine the effect of aging on the shear moduli of the superficial muscle heads of the quadriceps and to explore its relationship with knee extension force. METHODS: Passive shear moduli of the rectus femoris (RF), vastus lateralis (VL), and vastus medialis (VM) were measured at rest using shear wave elastography in 20 young and 20 senior female adults. Measurements were repeated at four knee joint positions, that is, 30°, 60°, 90°, and 105° of knee flexion. Maximal isometric voluntary knee extension force was assessed at 30°, 60°, and 90° of knee flexion. RESULTS: As per our findings, senior adults were determined to have significantly higher passive muscle shear moduli in the RF (by 34% – 68%; all p < 0.05) and the VL muscle heads (by 13%–16%, all p < 0.05) at and beyond 60° of knee flexion. Age-related increase in the VM was evident at 105° knee flexion (by11%, p = 0.020). The RF shear modulus was negatively correlated to the maximal isometric voluntary contraction force measured at 60° (r = − 0.485, p = 0.030) in senior adults. CONCLUSIONS: Senior female adults had greater passive stiffness at the superficial muscle heads of the quadriceps muscles when measured at long muscle length. Among the senior female adults, the passive stiffness of RF has been determined to have a negative association with the knee extensor force only at 60° knee flexion. No significant association was noted for other angles and muscles. |
format | Online Article Text |
id | pubmed-8477537 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-84775372021-09-29 Age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females Xu, Jingfei Fu, Siu Ngor Hug, François BMC Musculoskelet Disord Research BACKGROUND: In aging, muscle stiffness is considered as one of the factors associated with the reduction of force generation capability. There have been inconsistent findings on age-related alteration in the passive stiffness of quadriceps muscle in the female adults. Thus, the aim of this study was to determine the effect of aging on the shear moduli of the superficial muscle heads of the quadriceps and to explore its relationship with knee extension force. METHODS: Passive shear moduli of the rectus femoris (RF), vastus lateralis (VL), and vastus medialis (VM) were measured at rest using shear wave elastography in 20 young and 20 senior female adults. Measurements were repeated at four knee joint positions, that is, 30°, 60°, 90°, and 105° of knee flexion. Maximal isometric voluntary knee extension force was assessed at 30°, 60°, and 90° of knee flexion. RESULTS: As per our findings, senior adults were determined to have significantly higher passive muscle shear moduli in the RF (by 34% – 68%; all p < 0.05) and the VL muscle heads (by 13%–16%, all p < 0.05) at and beyond 60° of knee flexion. Age-related increase in the VM was evident at 105° knee flexion (by11%, p = 0.020). The RF shear modulus was negatively correlated to the maximal isometric voluntary contraction force measured at 60° (r = − 0.485, p = 0.030) in senior adults. CONCLUSIONS: Senior female adults had greater passive stiffness at the superficial muscle heads of the quadriceps muscles when measured at long muscle length. Among the senior female adults, the passive stiffness of RF has been determined to have a negative association with the knee extensor force only at 60° knee flexion. No significant association was noted for other angles and muscles. BioMed Central 2021-09-27 /pmc/articles/PMC8477537/ /pubmed/34579696 http://dx.doi.org/10.1186/s12891-021-04519-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Xu, Jingfei Fu, Siu Ngor Hug, François Age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females |
title | Age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females |
title_full | Age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females |
title_fullStr | Age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females |
title_full_unstemmed | Age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females |
title_short | Age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females |
title_sort | age-related increase in muscle stiffness is muscle length dependent and associated with muscle force in senior females |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477537/ https://www.ncbi.nlm.nih.gov/pubmed/34579696 http://dx.doi.org/10.1186/s12891-021-04519-8 |
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