Bone marrow-derived mesenchymal stem cells combined with gonadotropin therapy restore postnatal oogenesis of chemo-ablated ovaries in rats via enhancing very small embryonic-like stem cells

BACKGROUND: Very small embryonic-like stem cells (VSELs) are a rare population within the ovarian epithelial surface. They contribute to postnatal oogenesis as they have the ability to generate immature oocytes and resist the chemotherapy. These cells express markers of pluripotent embryonic and pri...

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Detalles Bibliográficos
Autores principales: Ebrahim, Nesrine, Al Saihati, Hajir A., Shaman, Amani, Dessouky, Arigue A., Farid, Ayman Samir, Hussien, Noha I., Mostafa, Ola, Seleem, Yasmin, Sabry, Dina, Saad, Ahmed S., Emam, Hanan Tawfeek, Hassouna, Amira, Badr, Omnia A. M., Saffaf, Bayan A., Forsyth, Nicholas R., Salim, Rabab F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477571/
https://www.ncbi.nlm.nih.gov/pubmed/34579781
http://dx.doi.org/10.1186/s13287-021-02415-5

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