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Global Pattern of CD8(+) T-Cell Infiltration and Exhaustion in Colorectal Cancer Predicts Cancer Immunotherapy Response

Background: The MSI/MSS status does not fully explain cancer immunotherapy response in colorectal cancer. Thus, we developed a colorectal cancer-specific method that predicts cancer immunotherapy response. Methods: We used gene expression data of 454 samples (MSI = 131, MSI-L = 23, MSS = 284, and Un...

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Detalles Bibliográficos
Autores principales:	Tian, Sun, Wang, Fulong, Zhang, Rongxin, Chen, Gong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477790/ https://www.ncbi.nlm.nih.gov/pubmed/34594218 http://dx.doi.org/10.3389/fphar.2021.715721

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