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High-Grade Intraventricular Astroblastoma in a Young Adult: A Rare and Controversial Tumor to Manage

Astroblastoma is a rare primary central nervous system tumor of controversial site of origin. They account for 0.45-2.8% of all primary neuroepithelial central nervous system. It has been reported in paediatric age group with bimodal age distribution affecting more females with male to female ratio...

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Autores principales: Singh, Karuna, Garg, Shipra, Rani, Shilp, Sandhu, Parvinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477834/
https://www.ncbi.nlm.nih.gov/pubmed/34660370
http://dx.doi.org/10.4103/ajns.AJNS_430_20
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author Singh, Karuna
Garg, Shipra
Rani, Shilp
Sandhu, Parvinder
author_facet Singh, Karuna
Garg, Shipra
Rani, Shilp
Sandhu, Parvinder
author_sort Singh, Karuna
collection PubMed
description Astroblastoma is a rare primary central nervous system tumor of controversial site of origin. They account for 0.45-2.8% of all primary neuroepithelial central nervous system. It has been reported in paediatric age group with bimodal age distribution affecting more females with male to female ratio being 1:11. Astroblastomas are controversial and challenging tumors in terms of diagnosis and therapeutics. Since it carries an unpredictable disease course it needs a regular follow up even for low grade tumor. Authors have tried various schedules of post op radiotherapy after maximum safe resection. Various chemotherapeutic drugs combination have also been tried without much success. We here report a 35 years old female patient who was diagnosed with high grade astroblastoma referred for post-operative radiotherapy after gross total resection. Since it is extremely rare tumor, its treatment still not well defined and also makes it difficult conduct studies to examine tumor characteristics.
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spelling pubmed-84778342021-10-14 High-Grade Intraventricular Astroblastoma in a Young Adult: A Rare and Controversial Tumor to Manage Singh, Karuna Garg, Shipra Rani, Shilp Sandhu, Parvinder Asian J Neurosurg Case Report Astroblastoma is a rare primary central nervous system tumor of controversial site of origin. They account for 0.45-2.8% of all primary neuroepithelial central nervous system. It has been reported in paediatric age group with bimodal age distribution affecting more females with male to female ratio being 1:11. Astroblastomas are controversial and challenging tumors in terms of diagnosis and therapeutics. Since it carries an unpredictable disease course it needs a regular follow up even for low grade tumor. Authors have tried various schedules of post op radiotherapy after maximum safe resection. Various chemotherapeutic drugs combination have also been tried without much success. We here report a 35 years old female patient who was diagnosed with high grade astroblastoma referred for post-operative radiotherapy after gross total resection. Since it is extremely rare tumor, its treatment still not well defined and also makes it difficult conduct studies to examine tumor characteristics. Wolters Kluwer - Medknow 2021-09-14 /pmc/articles/PMC8477834/ /pubmed/34660370 http://dx.doi.org/10.4103/ajns.AJNS_430_20 Text en Copyright: © 2021 Asian Journal of Neurosurgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Singh, Karuna
Garg, Shipra
Rani, Shilp
Sandhu, Parvinder
High-Grade Intraventricular Astroblastoma in a Young Adult: A Rare and Controversial Tumor to Manage
title High-Grade Intraventricular Astroblastoma in a Young Adult: A Rare and Controversial Tumor to Manage
title_full High-Grade Intraventricular Astroblastoma in a Young Adult: A Rare and Controversial Tumor to Manage
title_fullStr High-Grade Intraventricular Astroblastoma in a Young Adult: A Rare and Controversial Tumor to Manage
title_full_unstemmed High-Grade Intraventricular Astroblastoma in a Young Adult: A Rare and Controversial Tumor to Manage
title_short High-Grade Intraventricular Astroblastoma in a Young Adult: A Rare and Controversial Tumor to Manage
title_sort high-grade intraventricular astroblastoma in a young adult: a rare and controversial tumor to manage
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477834/
https://www.ncbi.nlm.nih.gov/pubmed/34660370
http://dx.doi.org/10.4103/ajns.AJNS_430_20
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