Cargando…

Fn14-targeted BiTE and CAR-T cells demonstrate potent preclinical activity against glioblastoma

T cell-engaging therapies involving bispecific T cell engager (BiTE) and chimeric antigen receptor T (CAR-T) cells have achieved great success in the treatment of hematological tumors. However, the paucity of ideal cell surface molecules that can be targeted on glioblastoma (GBM) partially reduces t...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Gaowei, Zhang, Zongliang, Cai, Linjun, Tang, Xin, Huang, Jianhan, Yu, Lingyu, Wang, Guoqing, Zhong, Kunhong, Cao, Yi, Liu, Chang, Wang, Yuelong, Tong, Aiping, Zhou, Liangxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477963/
https://www.ncbi.nlm.nih.gov/pubmed/34595061
http://dx.doi.org/10.1080/2162402X.2021.1983306