Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data

Hypoxia adversely affects the pulmonary circulation of mammals, including vasoconstriction leading to elevated pulmonary arterial pressures. The clinical importance of changes in the structure and function of the large, elastic pulmonary arteries is gaining increased attention, particularly regardin...

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Detalles Bibliográficos
Autores principales: Manning, Edward P., Ramachandra, Abhay B., Schupp, Jonas C., Cavinato, Cristina, Raredon, Micha Sam Brickman, Bärnthaler, Thomas, Cosme, Carlos, Singh, Inderjit, Tellides, George, Kaminski, Naftali, Humphrey, Jay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478173/
https://www.ncbi.nlm.nih.gov/pubmed/34594238
http://dx.doi.org/10.3389/fphys.2021.726253

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