Characterization of the NiRAN domain from RNA-dependent RNA polymerase provides insights into a potential therapeutic target against SARS-CoV-2

Apart from the canonical fingers, palm and thumb domains, the RNA dependent RNA polymerases (RdRp) from the viral order Nidovirales possess two additional domains. Of these, the function of the Nidovirus RdRp associated nucleotidyl transferase domain (NiRAN) remains unanswered. The elucidation of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Dwivedy, Abhisek, Mariadasse, Richard, Ahmad, Mohammed, Chakraborty, Sayan, Kar, Deepsikha, Tiwari, Satish, Bhattacharyya, Sankar, Sonar, Sudipta, Mani, Shailendra, Tailor, Prafullakumar, Majumdar, Tanmay, Jeyakanthan, Jeyaraman, Biswal, Bichitra Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478224/
https://www.ncbi.nlm.nih.gov/pubmed/34516563
http://dx.doi.org/10.1371/journal.pcbi.1009384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478224/
https://www.ncbi.nlm.nih.gov/pubmed/34516563
http://dx.doi.org/10.1371/journal.pcbi.1009384

Ejemplares similares