Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery

[Image: see text] Bacterial resistance to antibiotics makes previously manageable infections again disabling and lethal, highlighting the need for new antibacterial strategies. In this regard, inhibition of the bacterial division process by targeting key protein FtsZ has been recognized as an attrac...

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Detalles Bibliográficos
Autores principales: Huecas, Sonia, Araújo-Bazán, Lidia, Ruiz, Federico M., Ruiz-Ávila, Laura B., Martínez, R. Fernando, Escobar-Peña, Andrea, Artola, Marta, Vázquez-Villa, Henar, Martín-Fontecha, Mar, Fernández-Tornero, Carlos, López-Rodríguez, María L., Andreu, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478281/
https://www.ncbi.nlm.nih.gov/pubmed/33908781
http://dx.doi.org/10.1021/acs.jmedchem.0c02207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478281/
https://www.ncbi.nlm.nih.gov/pubmed/33908781
http://dx.doi.org/10.1021/acs.jmedchem.0c02207

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