Detecting Heterogeneity of Intervention Effects Using Analysis and Meta-analysis of Differences in Variance Between Trial Arms

Randomized controlled trials (RCTs) with continuous outcomes usually only examine mean differences in response between trial arms. If the intervention has heterogeneous effects, then outcome variances will also differ between arms. Power of an individual trial to assess heterogeneity is lower than t...

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Detalles Bibliográficos
Autores principales: Mills, Harriet L., Higgins, Julian P.T., Morris, Richard W., Kessler, David, Heron, Jon, Wiles, Nicola, Davey Smith, George, Tilling, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478324/
https://www.ncbi.nlm.nih.gov/pubmed/34432720
http://dx.doi.org/10.1097/EDE.0000000000001401

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