In Silico Prediction of the Toxic Potential of Neuroprotective Bifunctional Molecules Based on Chiral N-Propargyl-1,2-amino Alcohol Derivatives

[Image: see text] N-Propargylamines are useful synthetic scaffolds for the synthesis of bioactive molecules, and in addition, they possess important pharmacological activities. We obtained several neuroprotective molecules, chiral 1,2-amino alcohols and 1,2-diamines, able to reduce by almost 70% the...

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Detalles Bibliográficos
Autores principales: Ramos, Eva, Lajarín-Cuesta, Rocío, Arribas, Raquel L., García-Frutos, Eva M., González-Lafuente, Laura, Egea, Javier, de los Ríos, Cristóbal, Romero, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478334/
https://www.ncbi.nlm.nih.gov/pubmed/33635058
http://dx.doi.org/10.1021/acs.chemrestox.0c00519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478334/
https://www.ncbi.nlm.nih.gov/pubmed/33635058
http://dx.doi.org/10.1021/acs.chemrestox.0c00519

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