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Lithium chloride prevents glucocorticoid-induced osteonecrosis of femoral heads and strengthens mesenchymal stem cell activity in rats

BACKGROUND: Accumulating evidence suggests that lithium influences mesenchymal stem cell (MSC) proliferation and osteogenic differentiation. As decreased bone formation in femoral heads is induced by glucocorticoids (GCs), we hypothesized that lithium has a protective effect on GC-induced osteonecro...

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Detalles Bibliográficos
Autores principales: Zhang, Yue-Lei, Zhu, Zhen-Zhong, Zhang, Le-Cheng, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478381/
https://www.ncbi.nlm.nih.gov/pubmed/34224402
http://dx.doi.org/10.1097/CM9.0000000000001530