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Lithium chloride prevents glucocorticoid-induced osteonecrosis of femoral heads and strengthens mesenchymal stem cell activity in rats
BACKGROUND: Accumulating evidence suggests that lithium influences mesenchymal stem cell (MSC) proliferation and osteogenic differentiation. As decreased bone formation in femoral heads is induced by glucocorticoids (GCs), we hypothesized that lithium has a protective effect on GC-induced osteonecro...
Autores principales: | Zhang, Yue-Lei, Zhu, Zhen-Zhong, Zhang, Le-Cheng, Wang, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478381/ https://www.ncbi.nlm.nih.gov/pubmed/34224402 http://dx.doi.org/10.1097/CM9.0000000000001530 |
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