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Frailty and Adverse Outcomes Among Older Patients Undergoing Gastroenterological Surgery in Vietnam
PURPOSE: With the ageing population, more older adults undergo surgery, and frailty increases the risk of postoperative complications in older patients. This study aimed to determine the association between frailty and 30-day adverse outcomes in older patients undergoing gastroenterological surgery...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478420/ https://www.ncbi.nlm.nih.gov/pubmed/34594108 http://dx.doi.org/10.2147/JMDH.S332986 |
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author | Than, The Ngoc Ha Nguyen, Thien Nguyen, Tran To Tran Pham, Tai |
author_facet | Than, The Ngoc Ha Nguyen, Thien Nguyen, Tran To Tran Pham, Tai |
author_sort | Than, The Ngoc Ha |
collection | PubMed |
description | PURPOSE: With the ageing population, more older adults undergo surgery, and frailty increases the risk of postoperative complications in older patients. This study aimed to determine the association between frailty and 30-day adverse outcomes in older patients undergoing gastroenterological surgery in Vietnam. PATIENTS AND METHODS: A prospective cohort study was conducted in the Gastroenterology Department of the University Medical Center in Ho Chi Minh City. Frailty was determined using Fried’s criteria. Adverse outcomes within 30 days of gastroenterological surgery were recorded, including postoperative infections, acute respiratory failure, acute kidney injury, and death. Univariate and multivariate logistic analyses were performed to determine the association between frailty and 30-day postoperative adverse outcomes using Stata 14.0. RESULTS: Data of 302 elective surgical participants were collected (mean age: 69.8± 8.1 years, 53.3% female), and the prevalence of frailty was 18.5%. Frailty was an independent risk factor for 30-day adverse outcomes (odds ratio=6.56, 95% confidence interval, 2.77–15.53, p<0.001), which included postoperative infections, acute respiratory failure, acute kidney injury, and death. Frail participants had a significantly higher risk of postoperative infections (odds ratio=8.21, 95% confidence interval, 3.28–20.54, p<0.001), and exhaustion was strongly associated with postoperative adverse outcomes. CONCLUSION: Frailty was a predictor of 30-day adverse outcomes in older patients undergoing gastroenterological surgery. Therefore, preoperative frailty should be screened in older patients, and frailty-associated risks should be considered during the decision-making process by physicians, patients, and their families. |
format | Online Article Text |
id | pubmed-8478420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-84784202021-09-29 Frailty and Adverse Outcomes Among Older Patients Undergoing Gastroenterological Surgery in Vietnam Than, The Ngoc Ha Nguyen, Thien Nguyen, Tran To Tran Pham, Tai J Multidiscip Healthc Original Research PURPOSE: With the ageing population, more older adults undergo surgery, and frailty increases the risk of postoperative complications in older patients. This study aimed to determine the association between frailty and 30-day adverse outcomes in older patients undergoing gastroenterological surgery in Vietnam. PATIENTS AND METHODS: A prospective cohort study was conducted in the Gastroenterology Department of the University Medical Center in Ho Chi Minh City. Frailty was determined using Fried’s criteria. Adverse outcomes within 30 days of gastroenterological surgery were recorded, including postoperative infections, acute respiratory failure, acute kidney injury, and death. Univariate and multivariate logistic analyses were performed to determine the association between frailty and 30-day postoperative adverse outcomes using Stata 14.0. RESULTS: Data of 302 elective surgical participants were collected (mean age: 69.8± 8.1 years, 53.3% female), and the prevalence of frailty was 18.5%. Frailty was an independent risk factor for 30-day adverse outcomes (odds ratio=6.56, 95% confidence interval, 2.77–15.53, p<0.001), which included postoperative infections, acute respiratory failure, acute kidney injury, and death. Frail participants had a significantly higher risk of postoperative infections (odds ratio=8.21, 95% confidence interval, 3.28–20.54, p<0.001), and exhaustion was strongly associated with postoperative adverse outcomes. CONCLUSION: Frailty was a predictor of 30-day adverse outcomes in older patients undergoing gastroenterological surgery. Therefore, preoperative frailty should be screened in older patients, and frailty-associated risks should be considered during the decision-making process by physicians, patients, and their families. Dove 2021-09-24 /pmc/articles/PMC8478420/ /pubmed/34594108 http://dx.doi.org/10.2147/JMDH.S332986 Text en © 2021 Than et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Than, The Ngoc Ha Nguyen, Thien Nguyen, Tran To Tran Pham, Tai Frailty and Adverse Outcomes Among Older Patients Undergoing Gastroenterological Surgery in Vietnam |
title | Frailty and Adverse Outcomes Among Older Patients Undergoing Gastroenterological Surgery in Vietnam |
title_full | Frailty and Adverse Outcomes Among Older Patients Undergoing Gastroenterological Surgery in Vietnam |
title_fullStr | Frailty and Adverse Outcomes Among Older Patients Undergoing Gastroenterological Surgery in Vietnam |
title_full_unstemmed | Frailty and Adverse Outcomes Among Older Patients Undergoing Gastroenterological Surgery in Vietnam |
title_short | Frailty and Adverse Outcomes Among Older Patients Undergoing Gastroenterological Surgery in Vietnam |
title_sort | frailty and adverse outcomes among older patients undergoing gastroenterological surgery in vietnam |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478420/ https://www.ncbi.nlm.nih.gov/pubmed/34594108 http://dx.doi.org/10.2147/JMDH.S332986 |
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