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QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS

OBJECTIVE: To quantify the neural elements in the posterior cruciate ligament (PCL) in healthy knees and with primary osteoarthrosis (OA). METHODS: In two groups with OA, one of cadavers and another of individuals, the area of neural elements identified in histological sections of PCL with anti-S100...

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Autores principales: OLIVEIRA, MARCELO PARENTE, MELLO, ROBERTO JOSÉ VIEIRA DE, MONTENEGRO, LUCIANO TAVARES, PAZ, SILVANIA TAVARES, LIMA, DIEGO ARIEL DE, LEITE, JOSÉ ALBERTO DIAS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ATHA EDITORA 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478427/
https://www.ncbi.nlm.nih.gov/pubmed/34629949
http://dx.doi.org/10.1590/1413-785220212905240286
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author OLIVEIRA, MARCELO PARENTE
MELLO, ROBERTO JOSÉ VIEIRA DE
MONTENEGRO, LUCIANO TAVARES
PAZ, SILVANIA TAVARES
LIMA, DIEGO ARIEL DE
LEITE, JOSÉ ALBERTO DIAS
author_facet OLIVEIRA, MARCELO PARENTE
MELLO, ROBERTO JOSÉ VIEIRA DE
MONTENEGRO, LUCIANO TAVARES
PAZ, SILVANIA TAVARES
LIMA, DIEGO ARIEL DE
LEITE, JOSÉ ALBERTO DIAS
author_sort OLIVEIRA, MARCELO PARENTE
collection PubMed
description OBJECTIVE: To quantify the neural elements in the posterior cruciate ligament (PCL) in healthy knees and with primary osteoarthrosis (OA). METHODS: In two groups with OA, one of cadavers and another of individuals, the area of neural elements identified in histological sections of PCL with anti-S100 immunohistochemistry was quantified. RESULTS: The overall mean area of the neural elements was 0.96% ± 0.67%, with the value in the cadaver group of 1.02% ± 0.67% and in the OA group of 0.80% ± 0.64%, with a significant statistically difference (p = 0.001). No correlation was observed between neural element quantification and the age of the individuals (p > 0.05). There was no difference in the quantification of neural elements between the sexes in the cadaver group (p = 0.766), but in the OA group there was a statistically significant reduction in males (p = 0.003). Also, in the osteoarthrosis group there was no difference in the quantification of neural elements in the knees with varus or valgus alignment (p = 0.847). CONCLUSION: There was a decrease in neural element quantification in PCL of individuals affected by OA in relation to non-arthritic individuals, with this quantification not related to age or with the axis of the lower limb. However, this quantification is not related to age or the axis of the lower limb.Level of Evidence III, Case control study.
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spelling pubmed-84784272021-10-08 QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS OLIVEIRA, MARCELO PARENTE MELLO, ROBERTO JOSÉ VIEIRA DE MONTENEGRO, LUCIANO TAVARES PAZ, SILVANIA TAVARES LIMA, DIEGO ARIEL DE LEITE, JOSÉ ALBERTO DIAS Acta Ortop Bras Original Article OBJECTIVE: To quantify the neural elements in the posterior cruciate ligament (PCL) in healthy knees and with primary osteoarthrosis (OA). METHODS: In two groups with OA, one of cadavers and another of individuals, the area of neural elements identified in histological sections of PCL with anti-S100 immunohistochemistry was quantified. RESULTS: The overall mean area of the neural elements was 0.96% ± 0.67%, with the value in the cadaver group of 1.02% ± 0.67% and in the OA group of 0.80% ± 0.64%, with a significant statistically difference (p = 0.001). No correlation was observed between neural element quantification and the age of the individuals (p > 0.05). There was no difference in the quantification of neural elements between the sexes in the cadaver group (p = 0.766), but in the OA group there was a statistically significant reduction in males (p = 0.003). Also, in the osteoarthrosis group there was no difference in the quantification of neural elements in the knees with varus or valgus alignment (p = 0.847). CONCLUSION: There was a decrease in neural element quantification in PCL of individuals affected by OA in relation to non-arthritic individuals, with this quantification not related to age or with the axis of the lower limb. However, this quantification is not related to age or the axis of the lower limb.Level of Evidence III, Case control study. ATHA EDITORA 2021 /pmc/articles/PMC8478427/ /pubmed/34629949 http://dx.doi.org/10.1590/1413-785220212905240286 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
OLIVEIRA, MARCELO PARENTE
MELLO, ROBERTO JOSÉ VIEIRA DE
MONTENEGRO, LUCIANO TAVARES
PAZ, SILVANIA TAVARES
LIMA, DIEGO ARIEL DE
LEITE, JOSÉ ALBERTO DIAS
QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS
title QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS
title_full QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS
title_fullStr QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS
title_full_unstemmed QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS
title_short QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS
title_sort quantification of neural elements in posterior cruciate ligament: comparison between healthy knees and with primary osteoarthrosis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478427/
https://www.ncbi.nlm.nih.gov/pubmed/34629949
http://dx.doi.org/10.1590/1413-785220212905240286
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