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Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients

We report a case of a 29-year-old woman admitted twice to our hospital with diabetic ketoacidosis (DKA) within 45 days following her bariatric surgery. The first admission required intensive care during her postoperative days after bariatric surgery. Subsequently, she continued to report high level...

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Autores principales: Moseley, Philip, Ahmed, Mohamed H, Owles, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478506/
https://www.ncbi.nlm.nih.gov/pubmed/34602795
http://dx.doi.org/10.1055/s-0041-1731139
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author Moseley, Philip
Ahmed, Mohamed H
Owles, Henry
author_facet Moseley, Philip
Ahmed, Mohamed H
Owles, Henry
author_sort Moseley, Philip
collection PubMed
description We report a case of a 29-year-old woman admitted twice to our hospital with diabetic ketoacidosis (DKA) within 45 days following her bariatric surgery. The first admission required intensive care during her postoperative days after bariatric surgery. Subsequently, she continued to report high level of ketones on a daily basis. At her second admission, she presented with all three criteria of DKA. She was treated with a standard protocol for DKA, but ketones plasma level remained high despite significant improvement in pH and glycemic control. The administration of thiamine replacement was associated with normalization of the hyperketonemia. Thiamine deficiency can be associated with bariatric surgery and can lead to high ketone level in individuals with type 1 diabetes.
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spelling pubmed-84785062021-10-01 Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients Moseley, Philip Ahmed, Mohamed H Owles, Henry J Lab Physicians We report a case of a 29-year-old woman admitted twice to our hospital with diabetic ketoacidosis (DKA) within 45 days following her bariatric surgery. The first admission required intensive care during her postoperative days after bariatric surgery. Subsequently, she continued to report high level of ketones on a daily basis. At her second admission, she presented with all three criteria of DKA. She was treated with a standard protocol for DKA, but ketones plasma level remained high despite significant improvement in pH and glycemic control. The administration of thiamine replacement was associated with normalization of the hyperketonemia. Thiamine deficiency can be associated with bariatric surgery and can lead to high ketone level in individuals with type 1 diabetes. Thieme Medical and Scientific Publishers Pvt. Ltd. 2021-09 2021-06-28 /pmc/articles/PMC8478506/ /pubmed/34602795 http://dx.doi.org/10.1055/s-0041-1731139 Text en The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Moseley, Philip
Ahmed, Mohamed H
Owles, Henry
Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_full Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_fullStr Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_full_unstemmed Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_short Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_sort recurrent diabetic ketoacidosis following bariatric surgery: the role of micronutrients
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478506/
https://www.ncbi.nlm.nih.gov/pubmed/34602795
http://dx.doi.org/10.1055/s-0041-1731139
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