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Diagnostic and Predictive Values of LAP in Hypertension: A Cross-Sectional Study in Chinese Population Older Than 65 Years

This study aimed to investigate the predictive value of lipid accumulation product (LAP) in hypertension in Chinese population older than 65 years. A total of 2092 adults from the communities in Pudong New Area of Shanghai were included in this cross-sectional study. The participants filled in quest...

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Autores principales: Yan, Shuo, Zheng, Qing-Hu, Sun, Dong-Mei, Wu, Ying, Li, Tu-Ming, Zhong, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478592/
https://www.ncbi.nlm.nih.gov/pubmed/34594579
http://dx.doi.org/10.1155/2021/3066007
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author Yan, Shuo
Zheng, Qing-Hu
Sun, Dong-Mei
Wu, Ying
Li, Tu-Ming
Zhong, Ping
author_facet Yan, Shuo
Zheng, Qing-Hu
Sun, Dong-Mei
Wu, Ying
Li, Tu-Ming
Zhong, Ping
author_sort Yan, Shuo
collection PubMed
description This study aimed to investigate the predictive value of lipid accumulation product (LAP) in hypertension in Chinese population older than 65 years. A total of 2092 adults from the communities in Pudong New Area of Shanghai were included in this cross-sectional study. The participants filled in questionnaire and received anthropometric and laboratory examinations. The receiver operating characteristics curve (ROC) was used to analyze the predictive value of different risk factors in hypertension. Results showed that LAP was closely related to hypertension (adjusted OR: 1.011, 95% CI: 1.007–1.015). In females, LAP, fasting blood glucose (FPG), and body mass index (BMI) were associated with hypertension; in males, triglycerides (TG) and waist circumference (WC) were related to hypertension. LAP (AUC = 0.655, 95% CI: 0.632–0.679) was better than neck circumference (NC) and BMI in predicting hypertension. When the cutoff value was 33.5, LAP had the best predictive performance. In males, LAP at 36.72 and 56.76 had the best predictive performance in males (AUC = 0.663, 95% CI: 0.629–0.697) and females (AUC = 0.650, 95% CI: 0.618–0.682), respectively. In conclusion, LAP is a risk factor of hypertension in the elderly. For hypertension, BMI, FPG, and LAP have favorable predictive performance in females, and WC and TG have better predictive performance in males.
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spelling pubmed-84785922021-09-29 Diagnostic and Predictive Values of LAP in Hypertension: A Cross-Sectional Study in Chinese Population Older Than 65 Years Yan, Shuo Zheng, Qing-Hu Sun, Dong-Mei Wu, Ying Li, Tu-Ming Zhong, Ping Int J Hypertens Research Article This study aimed to investigate the predictive value of lipid accumulation product (LAP) in hypertension in Chinese population older than 65 years. A total of 2092 adults from the communities in Pudong New Area of Shanghai were included in this cross-sectional study. The participants filled in questionnaire and received anthropometric and laboratory examinations. The receiver operating characteristics curve (ROC) was used to analyze the predictive value of different risk factors in hypertension. Results showed that LAP was closely related to hypertension (adjusted OR: 1.011, 95% CI: 1.007–1.015). In females, LAP, fasting blood glucose (FPG), and body mass index (BMI) were associated with hypertension; in males, triglycerides (TG) and waist circumference (WC) were related to hypertension. LAP (AUC = 0.655, 95% CI: 0.632–0.679) was better than neck circumference (NC) and BMI in predicting hypertension. When the cutoff value was 33.5, LAP had the best predictive performance. In males, LAP at 36.72 and 56.76 had the best predictive performance in males (AUC = 0.663, 95% CI: 0.629–0.697) and females (AUC = 0.650, 95% CI: 0.618–0.682), respectively. In conclusion, LAP is a risk factor of hypertension in the elderly. For hypertension, BMI, FPG, and LAP have favorable predictive performance in females, and WC and TG have better predictive performance in males. Hindawi 2021-09-21 /pmc/articles/PMC8478592/ /pubmed/34594579 http://dx.doi.org/10.1155/2021/3066007 Text en Copyright © 2021 Shuo Yan et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Yan, Shuo
Zheng, Qing-Hu
Sun, Dong-Mei
Wu, Ying
Li, Tu-Ming
Zhong, Ping
Diagnostic and Predictive Values of LAP in Hypertension: A Cross-Sectional Study in Chinese Population Older Than 65 Years
title Diagnostic and Predictive Values of LAP in Hypertension: A Cross-Sectional Study in Chinese Population Older Than 65 Years
title_full Diagnostic and Predictive Values of LAP in Hypertension: A Cross-Sectional Study in Chinese Population Older Than 65 Years
title_fullStr Diagnostic and Predictive Values of LAP in Hypertension: A Cross-Sectional Study in Chinese Population Older Than 65 Years
title_full_unstemmed Diagnostic and Predictive Values of LAP in Hypertension: A Cross-Sectional Study in Chinese Population Older Than 65 Years
title_short Diagnostic and Predictive Values of LAP in Hypertension: A Cross-Sectional Study in Chinese Population Older Than 65 Years
title_sort diagnostic and predictive values of lap in hypertension: a cross-sectional study in chinese population older than 65 years
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478592/
https://www.ncbi.nlm.nih.gov/pubmed/34594579
http://dx.doi.org/10.1155/2021/3066007
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