Luspatercept restores SDF-1-mediated hematopoietic support by MDS-derived mesenchymal stromal cells

The bone marrow microenvironment (BMME) plays a key role in the pathophysiology of myelodysplastic syndromes (MDS), clonal blood disorders affecting the differentiation, and maturation of hematopoietic stem and progenitor cells (HSPCs). In lower-risk MDS patients, ineffective late-stage erythropoies...

Descripción completa

Detalles Bibliográficos
Autores principales: Wobus, Manja, Mies, Anna, Asokan, Nandini, Oelschlägel, Uta, Möbus, Kristin, Winter, Susann, Cross, Michael, Weidner, Heike, Rauner, Martina, Hofbauer, Lorenz C., Bornhäuser, Martin, Platzbecker, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478655/
https://www.ncbi.nlm.nih.gov/pubmed/34002031
http://dx.doi.org/10.1038/s41375-021-01275-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478655/
https://www.ncbi.nlm.nih.gov/pubmed/34002031
http://dx.doi.org/10.1038/s41375-021-01275-5

Ejemplares similares