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Identification of neutralising pembrolizumab anti-drug antibodies in patients with melanoma
Development of anti-drug antibodies (ADAs) can interfere with therapeutic monoclonal antibodies and may lead to drug neutralisation and clinical disease progression. Measurement of circulating drug levels and development of ADAs in the setting of anti-programmed cell death-1 agent pembrolizumab has...
Autores principales: | Sasson, S. C., Wilkins, L. E., Watson, R. A., Jolly, C., Brain, O., Klenerman, P., Olsson-Brown, A., Fairfax, B. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478874/ https://www.ncbi.nlm.nih.gov/pubmed/34584157 http://dx.doi.org/10.1038/s41598-021-98700-7 |
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