TP53 mutants and non-HPV16/18 genotypes are poor prognostic factors for concurrent chemoradiotherapy in locally advanced cervical cancer

Targeted sequencing for somatic mutations across the hotspots of 50 cancer-related genes was performed using biopsy specimens to investigate whether clinicopathological factors and genomic alterations correlated with prognosis in locally advanced cervical cancer. Seventy patients diagnosed with Inte...

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Detalles Bibliográficos
Autores principales: Kuno, Ikumi, Takayanagi, Daisuke, Asami, Yuka, Murakami, Naoya, Matsuda, Maiko, Shimada, Yoko, Hirose, Sou, Kato, Mayumi Kobayashi, Komatsu, Masaaki, Hamamoto, Ryuji, Okuma, Kae, Kohno, Takashi, Itami, Jun, Yoshida, Hiroshi, Shiraishi, Kouya, Kato, Tomoyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478905/
https://www.ncbi.nlm.nih.gov/pubmed/34584128
http://dx.doi.org/10.1038/s41598-021-98527-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478905/
https://www.ncbi.nlm.nih.gov/pubmed/34584128
http://dx.doi.org/10.1038/s41598-021-98527-2

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