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TP53 mutants and non-HPV16/18 genotypes are poor prognostic factors for concurrent chemoradiotherapy in locally advanced cervical cancer

Targeted sequencing for somatic mutations across the hotspots of 50 cancer-related genes was performed using biopsy specimens to investigate whether clinicopathological factors and genomic alterations correlated with prognosis in locally advanced cervical cancer. Seventy patients diagnosed with Inte...

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Detalles Bibliográficos
Autores principales:	Kuno, Ikumi, Takayanagi, Daisuke, Asami, Yuka, Murakami, Naoya, Matsuda, Maiko, Shimada, Yoko, Hirose, Sou, Kato, Mayumi Kobayashi, Komatsu, Masaaki, Hamamoto, Ryuji, Okuma, Kae, Kohno, Takashi, Itami, Jun, Yoshida, Hiroshi, Shiraishi, Kouya, Kato, Tomoyasu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478905/ https://www.ncbi.nlm.nih.gov/pubmed/34584128 http://dx.doi.org/10.1038/s41598-021-98527-2

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