In vivo structure and dynamics of the SARS-CoV-2 RNA genome

The dynamics of SARS-CoV-2 RNA structure and their functional relevance are largely unknown. Here we develop a simplified SPLASH assay and comprehensively map the in vivo RNA-RNA interactome of SARS-CoV-2 genome across viral life cycle. We report canonical and alternative structures including 5′-UTR...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Huang, Kun, Xie, Dejian, Lau, Jian You, Shen, Wenlong, Li, Ping, Wang, Dong, Zou, Zhong, Shi, Shu, Ren, Hongguang, Wang, Youliang, Mao, Youzhi, Jin, Meilin, Kudla, Grzegorz, Zhao, Zhihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478942/
https://www.ncbi.nlm.nih.gov/pubmed/34584097
http://dx.doi.org/10.1038/s41467-021-25999-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478942/
https://www.ncbi.nlm.nih.gov/pubmed/34584097
http://dx.doi.org/10.1038/s41467-021-25999-1

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