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A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system

Gene therapy revolves around modifying genetic makeup by inserting foreign nucleic acids into targeted cells via gene delivery methods to treat a particular disease. While the genes targeted play a key role in gene therapy, the gene delivery system used is also of utmost importance as it determines...

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Detalles Bibliográficos
Autores principales: Kalidasan, V., Ng, Wai Hoe, Ishola, Oluwaseun Ayodeji, Ravichantar, Nithya, Tan, Jun Jie, Das, Kumitaa Theva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478948/
https://www.ncbi.nlm.nih.gov/pubmed/34584147
http://dx.doi.org/10.1038/s41598-021-98657-7