Cargando…
Design principles of collateral sensitivity-based dosing strategies
Collateral sensitivity (CS)-based antibiotic treatments, where increased resistance to one antibiotic leads to increased sensitivity to a second antibiotic, may have the potential to limit the emergence of antimicrobial resistance. However, it remains unclear how to best design CS-based treatment sc...
Autores principales: | Aulin, Linda B. S., Liakopoulos, Apostolos, van der Graaf, Piet H., Rozen, Daniel E., van Hasselt, J. G. Coen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479078/ https://www.ncbi.nlm.nih.gov/pubmed/34584086 http://dx.doi.org/10.1038/s41467-021-25927-3 |
Ejemplares similares
-
Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution
por: Liakopoulos, Apostolos, et al.
Publicado: (2022) -
Identification of antibiotic collateral sensitivity and resistance interactions in population surveillance data
por: Zwep, Laura B, et al.
Publicado: (2021) -
Biomarker‐Guided Individualization of Antibiotic Therapy
por: Aulin, Linda B.S., et al.
Publicado: (2021) -
Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations
por: Aulin, Linda B. S., et al.
Publicado: (2022) -
Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans
por: Aulin, Linda B. S., et al.
Publicado: (2018)