Cargando…
The Role of Substrate Mediated Allostery in the Catalytic Competency of the Bacterial Oligosaccharyltransferase PglB
The oligosaccharyltransferase of Campylobacter lari (PglB) catalyzes the glycosylation of asparagine in the consensus sequence N-X-S/T, where X is any residue except proline. Molecular dynamics simulations of PglB bound to two different substrates were used to characterize the differences in the str...
Autores principales: | Morgan, Brittany R., Massi, Francesca |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479172/ https://www.ncbi.nlm.nih.gov/pubmed/34604309 http://dx.doi.org/10.3389/fmolb.2021.740904 |
Ejemplares similares
-
Structure of bacterial oligosaccharyltransferase PglB bound to a reactive LLO and an inhibitory peptide
por: Napiórkowska, Maja, et al.
Publicado: (2018) -
Structural insights from random mutagenesis of Campylobacter jejuni oligosaccharyltransferase PglB
por: Ihssen, Julian, et al.
Publicado: (2012) -
Increased efficiency of Campylobacter jejuni N-oligosaccharyltransferase PglB by structure-guided engineering
por: Ihssen, Julian, et al.
Publicado: (2015) -
PglB function and glycosylation efficiency is temperature dependent when the pgl locus is integrated in the Escherichia coli chromosome
por: Terra, Vanessa S., et al.
Publicado: (2022) -
Dynamic allostery in thrombin—a review
por: Komives, Elizabeth A.
Publicado: (2023)