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K-RAS4A: Lead or Supporting Role in Cancer Biology?
The RAS oncogene is one of the most frequently mutated genes in human cancer, with K-RAS having a leading role in tumorigenesis. K-RAS undergoes alternative splicing, and as a result its transcript generates two gene products K-RAS4A and K-RAS4B, which are affected by the same oncogenic mutations, a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479197/ https://www.ncbi.nlm.nih.gov/pubmed/34604308 http://dx.doi.org/10.3389/fmolb.2021.729830 |