Monoclonal B-cell Lymphocytosis Exacerbated by Prednisolone Therapy for Dermatomyositis

Lymphoproliferative diseases have been associated with various autoimmune diseases. We experienced a case of non-chronic lymphocytic leukemia type monoclonal B-cell lymphocytosis (MBL) that was exacerbated by increasing prednisolone for dermatomyositis and then improved by decreasing the dosage. Bec...

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Detalles Bibliográficos
Autores principales: Kume, Ayaka, Kashiwakuma, Daisuke, Kubodera, Ai, Hayashi, Kiyohito, Shimizu, Ryo, Suzuki, Yoshio, Tanaka, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479216/
https://www.ncbi.nlm.nih.gov/pubmed/33746170
http://dx.doi.org/10.2169/internalmedicine.6956-20
Descripción
Sumario:Lymphoproliferative diseases have been associated with various autoimmune diseases. We experienced a case of non-chronic lymphocytic leukemia type monoclonal B-cell lymphocytosis (MBL) that was exacerbated by increasing prednisolone for dermatomyositis and then improved by decreasing the dosage. Because MBL is difficult to diagnose, cases like ours may not be rare. These findings will facilitate our understanding of the mechanism underlying lymphoproliferative diseases and autoimmune diseases.

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