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Knockdown of LRRN1 inhibits malignant phenotypes through the regulation of HIF-1α/Notch pathway in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most refractory and fatal human malignancies. Leucine-rich repeat neuronal protein-1 (LRRN1) plays a crucial role in the development of the nervous system. However, the clinical implications and biological functions of LRRN1 in PDAC remain unclea...

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Detalles Bibliográficos
Autores principales:	Zhang, Yalu, Liu, Qiaofei, Yang, Sen, Liao, Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479295/ https://www.ncbi.nlm.nih.gov/pubmed/34632050 http://dx.doi.org/10.1016/j.omto.2021.08.012

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