Dysregulation of cholesterol homeostasis in human lung cancer tissue and tumour-associated macrophages

BACKGROUND: Based on reports on elevated cholesterol levels in cancer cells, strategies to lower cholesterol synthesis have been suggested as an antitumour strategy. However, cholesterol depletion has also been shown to induce tumour-promoting actions in tumour-associated macrophages (TAMs). METHODS...

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Detalles Bibliográficos
Autores principales: Hoppstädter, Jessica, Dembek, Anna, Höring, Marcus, Schymik, Hanna S., Dahlem, Charlotte, Sultan, Afnan, Wirth, Natalie, Al-Fityan, Salma, Diesel, Britta, Gasparoni, Gilles, Walter, Jörn, Helms, Volkhard, Huwer, Hanno, Simon, Martin, Liebisch, Gerhard, Schulz, Marcel H., Kiemer, Alexandra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479395/
https://www.ncbi.nlm.nih.gov/pubmed/34571364
http://dx.doi.org/10.1016/j.ebiom.2021.103578

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