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Competing risks survival data under middle censoring—An application to COVID-19 pandemic
Survival data is being analysed here under the middle censoring scheme, using specifically quantile function modelling under competing risks. The use of middle censoring scheme has been shown to be very appropriate under the COVID-19 pandemic scenario. Cause-specific quantile inference under middle...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479409/ http://dx.doi.org/10.1016/j.health.2021.100006 |
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author | Rehman, H. Chandra, N. Jammalamadaka, S. Rao |
author_facet | Rehman, H. Chandra, N. Jammalamadaka, S. Rao |
author_sort | Rehman, H. |
collection | PubMed |
description | Survival data is being analysed here under the middle censoring scheme, using specifically quantile function modelling under competing risks. The use of middle censoring scheme has been shown to be very appropriate under the COVID-19 pandemic scenario. Cause-specific quantile inference under middle censoring is employed. Such quantile inferences are obtained through cumulative incidence function based on cause-specific proportional hazards model. The baseline lifetime is assumed to follow a very general parametric model namely the Weibull distribution, and is independent of the censoring mechanism. We obtain estimates of the unknown parameters and cause specific quantile functions under classical as well as a Bayesian set-up. A Monte Carlo simulation study assesses the relative performance of the different estimators. Finally, a real life data analysis is given for illustration of the proposed methods. |
format | Online Article Text |
id | pubmed-8479409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Author(s). Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84794092021-09-29 Competing risks survival data under middle censoring—An application to COVID-19 pandemic Rehman, H. Chandra, N. Jammalamadaka, S. Rao Healthcare Analytics Article Survival data is being analysed here under the middle censoring scheme, using specifically quantile function modelling under competing risks. The use of middle censoring scheme has been shown to be very appropriate under the COVID-19 pandemic scenario. Cause-specific quantile inference under middle censoring is employed. Such quantile inferences are obtained through cumulative incidence function based on cause-specific proportional hazards model. The baseline lifetime is assumed to follow a very general parametric model namely the Weibull distribution, and is independent of the censoring mechanism. We obtain estimates of the unknown parameters and cause specific quantile functions under classical as well as a Bayesian set-up. A Monte Carlo simulation study assesses the relative performance of the different estimators. Finally, a real life data analysis is given for illustration of the proposed methods. The Author(s). Published by Elsevier Inc. 2021-11 2021-09-28 /pmc/articles/PMC8479409/ http://dx.doi.org/10.1016/j.health.2021.100006 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Rehman, H. Chandra, N. Jammalamadaka, S. Rao Competing risks survival data under middle censoring—An application to COVID-19 pandemic |
title | Competing risks survival data under middle censoring—An application to COVID-19 pandemic |
title_full | Competing risks survival data under middle censoring—An application to COVID-19 pandemic |
title_fullStr | Competing risks survival data under middle censoring—An application to COVID-19 pandemic |
title_full_unstemmed | Competing risks survival data under middle censoring—An application to COVID-19 pandemic |
title_short | Competing risks survival data under middle censoring—An application to COVID-19 pandemic |
title_sort | competing risks survival data under middle censoring—an application to covid-19 pandemic |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479409/ http://dx.doi.org/10.1016/j.health.2021.100006 |
work_keys_str_mv | AT rehmanh competingriskssurvivaldataundermiddlecensoringanapplicationtocovid19pandemic AT chandran competingriskssurvivaldataundermiddlecensoringanapplicationtocovid19pandemic AT jammalamadakasrao competingriskssurvivaldataundermiddlecensoringanapplicationtocovid19pandemic |