Cargando…

Computational screening of phytochemicals from three medicinal plants as inhibitors of transmembrane protease serine 2 implicated in SARS-CoV-2 infection

BACKGROUND: SARS-CoV-2 infection or COVID-19 is a major global public health issue that requires urgent attention in terms of drug development. Transmembrane Protease Serine 2 (TMPRSS2) is a good drug target against SARS-CoV-2 because of the role it plays during the viral entry into the cell. Virtua...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oyedara, Omotayo O., Agbedahunsi, Joseph M., Adeyemi, Folasade M., Juárez-Saldivar, Alfredo, Fadare, Olatomide A., Adetunji, Charles O., Rivera, Gildardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). Published by Elsevier B.V. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479425/ https://www.ncbi.nlm.nih.gov/pubmed/35403085 http://dx.doi.org/10.1016/j.phyplu.2021.100135

Ejemplares similares

Transmembrane serine protease 2 is a prognostic factor for lung adenocarcinoma
por: Schneider, Marc A., et al.
Publicado: (2022)

Magnesium treatment on methylation changes of transmembrane serine protease 2 (TMPRSS2)
por: Fan, Lei, et al.
Publicado: (2021)

Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19
por: Posadas-Sánchez, Rosalinda, et al.
Publicado: (2022)

Potential Simultaneous Inhibitors of Angiotensin-Converting Enzyme 2 and Transmembrane Protease, Serine 2
por: Wu, Ching-Yuan, et al.
Publicado: (2020)

Docking study of transmembrane serine protease type 2 inhibitors for the treatment of COVID-19
por: Solanki, Naishadh
Publicado: (2022)

16S rRNA metagenomics data on the bacterial communities in integrated poultry-fish farm ponds
por: Akinde, Sunday B., et al.
Publicado: (2022)

Identification of novel transmembrane Protease Serine Type 2 drug candidates for COVID-19 using computational studies
por: Elbadwi, Fatima A., et al.
Publicado: (2021)

The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes
por: Ferrara, Francesca, et al.
Publicado: (2013)

Type II Transmembrane Serine Protease Gene Variants Associate with Breast Cancer
por: Luostari, Kaisa, et al.
Publicado: (2014)

Computational Analysis of Missense Variants in the Human Transmembrane Protease Serine 2 (TMPRSS2) and SARS-CoV-2
por: Saih, Asmae, et al.
Publicado: (2021)

rs12329760 Polymorphism in Transmembrane Serine Protease 2 Gene and Risk of Coronavirus Disease 2019 Mortality
por: Beheshti Shirazi, Saeedeh Sadat, et al.
Publicado: (2022)

Impacts of transmembrane serine protease 4 expression on susceptibility to severe acute respiratory syndrome coronavirus 2
por: Tan, Qi, et al.
Publicado: (2023)

Interaction of Protein C Inhibitor with the Type II Transmembrane Serine Protease Enteropeptidase
por: Prohaska, Thomas A., et al.
Publicado: (2012)

Intracellular autoactivation of TMPRSS11A, an airway epithelial transmembrane serine protease
por: Zhang, Ce, et al.
Publicado: (2020)

Evolutionary history of type II transmembrane serine proteases involved in viral priming
por: Forni, Diego, et al.
Publicado: (2022)

Type II Transmembrane Serine Proteases as Modulators in Adipose Tissue Phenotype and Function
por: Wu, Qingyu, et al.
Publicado: (2023)

Transmembrane protease serine 2 (TMPRSS2) rs75603675, comorbidity, and sex are the primary predictors of COVID-19 severity
por: Villapalos-García, Gonzalo, et al.
Publicado: (2022)

Angiotensin‐converting enzyme 2 and transmembrane protease serine 2 in female and male patients with end‐stage kidney disease
por: Arefin, Samsul, et al.
Publicado: (2022)

In-silico screening for identification of potential inhibitors against SARS-CoV-2 transmembrane serine protease 2 (TMPRSS2)
por: Barge, Sagar, et al.
Publicado: (2021)

TMEFF2 shedding is regulated by oxidative stress and mediated by ADAMs and transmembrane serine proteases implicated in prostate cancer
por: Gaweł‐Bęben, Katarzyna, et al.
Publicado: (2017)

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases
por: Kühn, Nora, et al.
Publicado: (2016)

Molecular mechanisms involved in anosmia induced by SARS-CoV-2, with a focus on the transmembrane serine protease TMPRSS2
por: Karimian, Ali, et al.
Publicado: (2022)

Correction: Transmembrane protease serine 2 (TMPRSS2) rs75603675, comorbidity and sex are the primary predictors of Covid-19 severity
por: Villapalos-García, Gonzalo, et al.
Publicado: (2022)

Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel’s γ-subunit
por: Sure, Florian, et al.
Publicado: (2022)

Transmembrane serine protease 2, a SARS-CoV-2 internalization protease, correlates with clinical outcome, molecular features, and immunotherapy response in colorectal cancer
por: Zhu, Chenjing, et al.
Publicado: (2023)

Anti-gastric cancer activity of 1,2,3-triazolo[4,5-d]pyrimidine hybrids (1,2,3-TPH): QSAR and molecular docking approaches
por: Kolawole, Oyebamiji Abel, et al.
Publicado: (2020)

Dysregulation of Type II Transmembrane Serine Proteases and Ligand-Dependent Activation of MET in Urological Cancers
por: Mukai, Shoichiro, et al.
Publicado: (2020)

Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A
por: Wang, Hongge, et al.
Publicado: (2019)

Transmembrane serine protease 2 and angiotensin-converting enzyme 2 anti-inflammatory receptors for COVID-19/inflammatory bowel diseases treatment
por: Lashgari, Naser-Aldin, et al.
Publicado: (2021)

Transmembrane serine protease TMPRSS2 implicated in SARS-CoV-2 infection is autoactivated intracellularly and requires N-glycosylation for regulation
por: Zhang, Yikai, et al.
Publicado: (2022)

Periodontitis promotes the expression of gingival transmembrane serine protease 2 (TMPRSS2), a priming protease for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
por: Ohnishi, Tomokazu, et al.
Publicado: (2022)

Protein expression of transmembrane protease serine 4 in the gastrointestinal tract and in healthy, cancer, and SARS-CoV-2 infected lungs
por: Kerslake, Rachel, et al.
Publicado: (2022)

The Transmembrane Protease Serine 2 (TMPRSS2) Non-Protease Domains Regulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike-Mediated Virus Entry
por: Strobelt, Romano, et al.
Publicado: (2023)

Synthesis and characterization of novel combretastatin analogues of 1,1-diaryl vinyl sulfones, with antiproliferative potential via in-silico and in-vitro studies
por: Egharevba, Godshelp O., et al.
Publicado: (2022)

TMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer
por: Kim, Semi
Publicado: (2023)

Transmembrane serine protease TADG-15 (ST14/Matriptase/MT-SP1): expression and prognostic value in ovarian cancer
por: Tanimoto, H, et al.
Publicado: (2005)

Pharmacoinformatics-based identification of transmembrane protease serine-2 inhibitors from Morus Alba as SARS-CoV-2 cell entry inhibitors
por: Shakya, Anshul, et al.
Publicado: (2021)

RAndomized Clinical Trial Of NAfamostat Mesylate, A Potent Transmembrane Protease Serine 2 (TMPRSS2) Inhibitor, in Patients with COVID-19 Pneumonia
por: Seccia, Teresa Maria, et al.
Publicado: (2023)

Nasopharyngeal Expression of Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 in Children within SARS-CoV-2-Infected Family Clusters
por: Hasan, Mohammad Rubayet, et al.
Publicado: (2021)

Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies
por: Kishk, Safaa M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1cukm9tnl2qbkog449ff89j8i5