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Resurfacing receptor binding domain of Colicin N to enhance its cytotoxic effect on human lung cancer cells

Colicin N (ColN) is a bacteriocin secreted by Escherichia coli (E. coli) to kill other Gram-negative bacteria by forcefully generating ion channels in the inner membrane. In addition to its bactericidal activity, ColN have been reported to selectively induce apoptosis in human lung cancer cells via...

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Detalles Bibliográficos
Autores principales: Arunmanee, Wanatchaporn, Duangkaew, Methawee, Taweecheep, Pornchanok, Aphicho, Kanokpol, Lerdvorasap, Panuwat, Pitchayakorn, Jesada, Intasuk, Chayada, Jiraratmetacon, Runglada, Syamsidi, Armini, Chanvorachote, Pithi, Chaotham, Chatchai, Pornputtapong, Natapol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479544/
https://www.ncbi.nlm.nih.gov/pubmed/34630940
http://dx.doi.org/10.1016/j.csbj.2021.09.008