Drug repurposing against breast cancer by integrating drug-exposure expression profiles and drug–drug links based on graph neural network

MOTIVATION: Breast cancer is one of the leading causes of cancer deaths among women worldwide. It is necessary to develop new breast cancer drugs because of the shortcomings of existing therapies. The traditional discovery process is time-consuming and expensive. Repositioning of clinically approved...

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Detalles Bibliográficos
Autores principales: Cui, Chen, Ding, Xiaoyu, Wang, Dingyan, Chen, Lifan, Xiao, Fu, Xu, Tingyang, Zheng, Mingyue, Luo, Xiaomin, Jiang, Hualiang, Chen, Kaixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479657/
https://www.ncbi.nlm.nih.gov/pubmed/33739367
http://dx.doi.org/10.1093/bioinformatics/btab191

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