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The gut microbiota instructs the hepatic endothelial cell transcriptome

The gut microbiota affects remote organ functions but its impact on organotypic endothelial cell (EC) transcriptomes remains unexplored. The liver endothelium encounters microbiota-derived signals and metabolites via the portal circulation. To pinpoint how gut commensals affect the hepatic sinusoida...

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Detalles Bibliográficos
Autores principales: Formes, Henning, Bernardes, Joana P., Mann, Amrit, Bayer, Franziska, Pontarollo, Giulia, Kiouptsi, Klytaimnistra, Schäfer, Katrin, Attig, Sebastian, Nikolova, Teodora, Hofmann, Thomas G., Schattenberg, Jörn M., Todorov, Hristo, Gerber, Susanne, Rosenstiel, Philip, Bopp, Tobias, Sommer, Felix, Reinhardt, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479694/
https://www.ncbi.nlm.nih.gov/pubmed/34622147
http://dx.doi.org/10.1016/j.isci.2021.103092