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The efficacy and safety of levilimab in severely ill COVID-19 patients not requiring mechanical ventilation: results of a multicenter randomized double-blind placebo-controlled phase III CORONA clinical study
OBJECTIVE AND DESIGN: The aim of this double-blind, placebo-controlled, phase III CORONA clinical trial was to evaluate the efficacy and safety of IL-6 receptor inhibitor levilimab (LVL) in subjects with severe COVID-19. SUBJECTS: The study included 217 patients. The eligible were men and non-pregna...
Autores principales: | Lomakin, Nikita V., Bakirov, Bulat A., Protsenko, Denis N., Mazurov, Vadim I., Musaev, Gaziyavdibir H., Moiseeva, Olga M., Pasechnik, Elena S., Popov, Vladimir V., Smolyarchuk, Elena A., Gordeev, Ivan G., Gilyarov, Mikhail Yu, Fomina, Darya S., Seleznev, Anton I., Linkova, Yulia N., Dokukina, Ekaterina A., Eremeeva, Anna V., Pukhtinskaia, Polina S., Morozova, Maria A., Zinkina-Orikhan, Arina V., Lutckii, Anton A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479713/ https://www.ncbi.nlm.nih.gov/pubmed/34586459 http://dx.doi.org/10.1007/s00011-021-01507-5 |
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