Insulin Crystals Grown in Short-Peptide Supramolecular Hydrogels Show Enhanced Thermal Stability and Slower Release Profile

[Image: see text] Protein therapeutics have a major role in medicine in that they are used to treat diverse pathologies. Their three-dimensional structures not only offer higher specificity and lower toxicity than small organic compounds but also make them less stable, limiting their in vivo half-li...

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Detalles Bibliográficos
Autores principales: Contreras-Montoya, Rafael, Arredondo-Amador, María, Escolano-Casado, Guillermo, Mañas-Torres, Mari C., González, Mercedes, Conejero-Muriel, Mayte, Bhatia, Vaibhav, Díaz-Mochón, Juan J., Martínez-Augustin, Olga, de Medina, Fermín Sánchez, Lopez-Lopez, Modesto T., Conejero-Lara, Francisco, Gavira, José A., de Cienfuegos, Luis Álvarez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479728/
https://www.ncbi.nlm.nih.gov/pubmed/33661596
http://dx.doi.org/10.1021/acsami.1c00639

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