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Traumatic brain injury induces region-specific glutamate metabolism changes as measured by multiple mass spectrometry methods

The release of excess glutamate following traumatic brain injury (TBI) results in glutamate excitotoxicity and metabolic energy failure. Endogenous mechanisms for reducing glutamate concentration in the brain parenchyma following TBI are poorly understood. Using multiple mass spectrometry approaches...

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Detalles Bibliográficos
Autores principales: Sowers, James L., Sowers, Mark L., Shavkunov, Alexander S., Hawkins, Bridget E., Wu, Ping, DeWitt, Douglas S., Prough, Donald S., Zhang, Kangling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479783/
https://www.ncbi.nlm.nih.gov/pubmed/34622161
http://dx.doi.org/10.1016/j.isci.2021.103108

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