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Protocol for the Stimulating β(3)-Adrenergic Receptors for Peripheral Artery Disease (STAR-PAD) trial: a double-blinded, randomised, placebo-controlled study evaluating the effects of mirabegron on functional performance in patients with peripheral arterial disease
INTRODUCTION: There is currently only one approved medication effective at improving walking distance in people with intermittent claudication. Preclinical data suggest that the β(3)-adrenergic receptor agonist (mirabegron) could be repurposed to treat intermittent claudication associated with perip...
Autores principales: | Bubb, Kristen J, Harmer, Jason A, Finemore, Meghan, Aitken, Sarah Joy, Ali, Zara S, Billot, Laurent, Chow, Clara, Golledge, Jonathan, Mister, Rebecca, Gray, Michael P, Grieve, Stuart M, Hamburg, Naomi, Keech, Anthony C, Patel, Sanjay, Puttaswamy, Vikram, Figtree, Gemma A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479946/ https://www.ncbi.nlm.nih.gov/pubmed/34588252 http://dx.doi.org/10.1136/bmjopen-2021-049858 |
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