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Early life and adult stress promote sex dependent changes in hypothalamic miRNAs and environmental enrichment prevents stress-induced miRNA and gene expression changes in rats

BACKGROUND: The hypothalamus plays a key role in the stress response. While early life stress (ELS) increases susceptibility to psychiatric disorders including major depressive disorder (MDD), acute stress during adulthood can also precipitate MDD after ELS. AIM: Here, we tested the expression of mi...

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Detalles Bibliográficos
Autores principales: McKibben, Lauren Allen, Dwivedi, Yogesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480023/
https://www.ncbi.nlm.nih.gov/pubmed/34583641
http://dx.doi.org/10.1186/s12864-021-08003-4